Pull off I-95 to find a welcoming retreat at the Park Inn by Radisson Florence, SC, situated minutes from downtown and the Florence Center. Guests in town for medical appointments appreciate that we’re just 10 minutes from McLeod Regional Medical Center. Traveling by air? Florence Regional Airport (FLO) is approximately six miles away.

The Quality Inn® West Columbia – Cayce hotel in West Columbia is conveniently located off U.S. Highway 321 and Interstate 26—less than 15 minutes from Columbia Metropolitan Airport. Students and their families will appreciate our proximity to the University of South Carolina. Guests can also enjoy easy access to area attractions like the South Carolina State House, Riverbanks Zoo & Garden, South Carolina State Museum, EdVenture Children’s Museum, the Columbia Museum of Art, Colonial Life Arena and more.

The Quality Inn® in Union is a welcoming destination for the business or solo traveler looking for a top hotel at a value. Located off U.S. Route 176 near the Union County Dragway, our property offers easy access to historical sites, sports destinations and key local businesses. Our friendly staff is always available to assist you in planning activities. A stay at our hotel means a chance to experience a wide range of activities that travelers of all ages will enjoy.

Located along one of the city’s main retail corridors and only 20 minutes from downtown, our Cambria® Hotel Greenville offers upscale accommodations in the heart of Upstate South Carolina. We’re within walking distance of Whole Foods and other stores at The Point shopping plaza, and just a short drive from popular attractions like the Bon Secours Wellness Arena, Fluor Field, and the Clemson University International Center for Automotive Research.

The Sleep Inn® hotel in Spartanburg, SC, is a great place to get the restful stay you deserve while traveling. Find our 100% smoke-free hotel just off Interstate 26. Start your morning with free hot breakfast and free coffee in our lobby and access the free WiFi to check email and keep up with the world. At our warm and welcoming hotel with simply stylish rooms, we’ll make sure your stay is as cozy and refreshing as possible.

The Cambria® Hotel Summerville offers thoughtful amenities and little luxuries designed to make your stay feel indulgent. Located in the heart of Summerville—with Charleston and Mount Pleasant close by—our hotel is within easy reach of many popular attractions. You’ll enjoy amenities like a full-service restaurant and bar, a seasonal outdoor pool, a fitness center and free parking. WiFi is also included throughout the hotel. Our spacious guest rooms feature spa-inspired bathrooms, a refrigerator, a microwave, a flat-screen TV and stylish décor inspired by the beauty of Carolina Lowcountry.

For a comfortable stay near Five Points and Fort Jackson, choose the Country Inn & Suites by Radisson, Columbia, SC. Our location just off I-77 makes it easy to reach Williams-Brice Stadium to cheer on the USC Gamecocks or spend an afternoon at Riverbanks Zoo & Garden. Here for medical appointments? William Jennings Bryan Dorn Department of Veterans Affairs Medical Center is only one mile away.

Enjoy professional service, boutique accommodations and a convenient location minutes from Patriot’s Point, USS Yorktown and downtown Charleston. The Inn at I’On, Ascend Hotel Collection® is a charming hotel located in Mount Pleasant’s I’On community. Our front desk is open from 7 a.m. to 7 p.m. daily. If you’re arriving outside these hours, please contact the hotel directly to make arrangements accordingly.

At our Comfort Inn & Suites® Greer – Greenville hotel, we provide the relaxing accommodations and travel amenities you need for a great stay. We’re a smoke-free hotel near several attractions like downtown Greer with its many restaurants, landmarks and shops. As our guest, you’ll get to enjoy a free hot breakfast every morning with refreshing juices and healthy options to jumpstart a day of activities. We have a reception desk staffed 24 hours a day. Break a sweat and keep fit in the fitness center or enjoy a refreshing swim session in the outdoor pool.

The Econo Lodge® in Clemson, SC, has the basics for travelers like free WiFi to check your email and affordable rates to keep your stay easy on your wallet. We also serve free coffee to all our guests to make sure you’ll stay awake for your day on the road. Vending machines are also available so you can stock up on snacks and drinks before you head into Clemson.

The Quality Inn & Suites® in Aiken, SC, is a great place to get more for your money. You can find us south of Interstate 20 right in the heart of southern Aiken. Plenty of dining options are close by, and Hopeland Gardens is only 2 miles away. At our pet-friendly hotel, you’ll enjoy a complimentary breakfast to start your day. Free WiFi will keep you connected through your stay.

Thrive while you’re away from home at our Suburban Studios® extended-stay hotel off I-26 in Orangeburg, SC. Whether you need accommodations for a week, a month or longer, we’ve got you covered with apartment-style amenities. Settle into your guest room with a full kitchen and free WiFi. We’re also pet-friendly, allowing you to feel more at home. Then, you’ll be a short distance to great hiking areas, shopping malls, university campuses and more.

Our Econo Lodge® Black Hills hotel in Rapid City is an easy stop on the road with affordable rates within close proximity of the area’s top attractions. Our location off Interstate 90 makes it easy to get to where you would like to go, whether visiting for business or pleasure. Our hotel is close to the Rapid City Regional Airport, which is about 20 minutes away.

Situated off I-26 about five minutes from Columbia Metropolitan Airport (CAE), the Country Inn & Suites by Radisson, Columbia Airport, SC offers an affordable stay for your vacation or business trip to Cayce. Whether you’re coming or going, our complimentary shuttle provides seamless transportation to and from the CAE airport, and we offer free parking for those driving in.

Econo Lodge® in Sioux Falls provides the hotel experience that simplifies travel — an easy stop on the road where you can find a great place to stay. And all at a great rate, too. You’ll find us off Interstate 90 just minutes from the Sioux Falls Regional Airport, making it simple to fly in and out of the area.

Welcome to our newly renovated Quality Inn & Suites® Columbia Harbison hotel. We’re conveniently located off I-26 in the liveliest part of Columbia, SC, next door to boundless shopping, dining and entertainment at Columbiana Centre mall — plus only minutes away from Lake Murray and Downtown Columbia. You’ll experience a true value here, thanks to amenities like free WiFi, hot breakfast, a fitness center, free parking and more.

Live like home while you’re away at our newly renovated MainStay Suites® Columbia Harbison hotel in South Carolina. We’re located right off I-26 in the Harbison neighborhood, just 10 minutes from Downtown Columbia. To make your extended stay even more convenient, we’re right next door to plenty of restaurants and less than half a mile to Columbia Centre Mall. Our spacious guest rooms feature a fully-equipped kitchen and free WiFi, so you can maintain all your daily routines for as long as you need.

Get more for your money at Quality Inn & Suites® South. Our pet-friendly hotel in Sioux Falls offers professional service at a great value, allowing you to focus on making the most of your travels. We’re conveniently located near some of the most popular Sioux Falls attractions including Wild Water West Waterpark, South Dakota’s largest waterpark. We’re also a quick drive from Great Bear Ski Valley, Huset’s Speedway and the Siouxland Heritage Museum.

Enjoy the rushing waters of Sioux Falls when you stay with us at Comfort Suites®. Located off Interstate 29, our convenient hotel is across the street from the shops at Empire Mall. You’ll find modern guest rooms and friendly staff while you stay at this South Dakota hotel. Guests visiting the University of Sioux Falls will love the fact that our suites are less than 3 miles away from campus. All travelers come to the area for its popular attractions, including the Sertoma Butterfly House, Great Plains Zoo & Delbridge Museum and the Washington Pavilion of Arts and Science. Many of Sioux Falls’ beautiful parks and trails that line the river are less than a mile from our excellent accommodations.

For your next trip to the state capital, choose the Country Inn & Suites by Radisson, Columbia at Harbison, SC near the suburb of Irmo. Our location off I-26 makes it easy to reach downtown Columbia and attractions like Riverbanks Zoo & Garden in about 15 minutes. If you’re visiting a loved one at Fort Jackson or the University of South Carolina, you’ll appreciate a short commute to both.

The Country Inn & Suites by Radisson, Aiken, SC places you just outside the city’s historic downtown, a pedestrian-friendly area brimming with charming restaurants, shops, and art galleries. To escape the city bustle, explore the paths at Hopelands Gardens, a 14-acre oasis located just outside the city proper, or tee off at local greens, such as Cedar Creek Golf Club and The Aiken Golf Club.

Whether you’re visiting a college campus or just passing through on I-85, the Country Inn & Suites by Radisson, Anderson, SC is perfectly positioned for your Upstate adventures. You can reach Clemson’s Memorial Stadium in less than 30 minutes via Highway 76, or you can head about 20 minutes southeast into downtown Anderson to tour Anderson University. For fun in the sun, visit Lake Hartwell.

The Country Inn & Suites by Radisson, Murrells Inlet, SC off Highway 17 Bypass places you about 15 miles south of Myrtle Beach and just minutes from the shops, seafood restaurants, and lively bars along the MarshWalk. Charter a fishing boat at Crazy Sister Marina for deep-sea excursions, or head to the award-winning Brookgreen Gardens to admire a collection of outdoor sculptures.

Whether you’re visiting Port Royal Island for a beach vacation or a golf getaway, the Country Inn & Suites by Radisson, Beaufort West, SC provides a comfortable stay just off US 21 Business. Our hotel is about three miles from stately antebellum mansions and boutique shopping in the heart of Beaufort. Coastal fun awaits on the nearby waterways and beaches of South Carolina’s Sea Islands.

Located just off US 501, the Country Inn & Suites by Radisson, Myrtle Beach, SC welcomes business and leisure travelers alike to the Grand Strand. Guests flying into Myrtle Beach International Airport (MYR) can drive just 10 minutes to the hotel, where you’ll enjoy quick access to area activities, from practicing your swing at River Oaks Golf Club to sunbathing at beaches also just 10 minutes away.

When you stay at our stylist Sleep Inn® Airport hotel in Sioux Falls, you’ll find a restful location where you can unwind after a long drive and explore the exciting area. We are conveniently situated near Interstate 29 and the Sioux Falls Regional Airport (also known as Joe Foss Field). Our hotel is an excellent choice for those in town to drop off a child at the University of Sioux Falls or catch a sports game or concert at the Sioux Falls Arena.

Hop off the plane and into the heart of Midwestern hospitality at Quality Inn® Aberdeen, close to Aberdeen Regional Airport. When you stay with us, you’ll get more for your money with our friendly service and convenient amenities like an indoor pool and exercise room. We also offer guest laundry facilities so you can spend less time packing your entire wardrobe and more time enjoying your trip. Don’t forget to start your day with a free hot breakfast and plenty of coffee.

Experience the gorgeous natural scenery in Pierre during your stay at Quality Inn® Pierre-Fort Pierre. Our pet-friendly hotel in South Dakota’s capital offers convenient amenities, a great value and the friendly service that South Dakota is known for. When you stay with us, you can expect friendly service and helpful little extras to help you get more for your money. Plus, we’re located mere minutes away from the Pierre Regional Airport and other local destinations.

Family fun is right on the property at our Comfort Inn & Suites® Deadwood hotel in the Black Hills, a historic Western town. Our arcade boasts more than 25 games. Enjoy a cocktail at the full-service bar, and nosh on nachos and pizza at the in-house restaurant. Don’t miss our big backyard, where you can hike or relax by the creek, play free yard games like ladder ball and bocce ball, relax by a bonfire and play a round at our 18-hole mini-golf course.

At Comfort Inn & Suites®, we offer spacious suites and soothing amenities to help you relax and enjoy your stay. Start your day with our signature free hot breakfast and enjoy a free cup of coffee, free bottled water and free cookies in our welcoming lobby. Our indoor pool and fitness center help you stay active while you travel, while our business center and free WiFi make it easy to be productive while you’re away. We offer an outdoor patio so you can soak up the sunshine and guest laundry facilities so you can wash and dry your clothes after exploring the Black Hills.